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Pathology and Genetics: Tumours of Haematopoietic and Lymphoid Tissues (World Health Organization Classification of Tumours) by Elaine Sarkin Jaffe

Pathology and Genetics: Tumours of Haematopoietic and Lymphoid Tissues (World Health Organization Classification of Tumours) Elaine Sarkin Jaffe ebook
Format: pdf
Page: 352
Publisher:
ISBN: 9283224116, 9789283224112

(2001) in World Health Organization Classification of Tumours. Book Description WHO Classification of Tumours of Haematopoietic and Lymphoid Tissue is the third volume in the new WHO series on histological and genetic typing of human tumors. Oesophageal SCC is defined as the pen-etration of neoplastic squamous epitheli-um through the epithelial basement mem-brane and extension into the lamina pro-pria or deeper tissue layers. It provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies monitoring response to therapy and clinical outcome. Pathology and Genetics of Tumors of Haematopoietic and Lymphoid Tissues. Tumours of the Digestive System Edited by. Extra-nodal NK/T -cell lymphoma (ENKTL) is a relatively recently characterised clinicopathological entity, being formally incorporated into the WHO classification of haematopoietic and lymphoid tumours in 1999 [86]. World Health Organization Classification of Tumours International Agency for Research on Cancer (IARC) Pathology and Genetics of. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. The criteria currently used to distinguish between Burkitt lymphoma (BL) and DLBCL, is based on differences in morphology, immunophenotype, and genetic abnormalities. Within the GC B cell reaction or maintenance of mature B cells additional factors are involved including IL21, CD40L (TNFSF5 / CD154) or tumour necrosis factor superfamily member 13b (BAFF / TNFSF13b / CD257) [2,4-6,8]. There followed a series of reports, predominantly from Japan and East Asia, demonstrating the striking pathological feature of EBV-infected T or NK cells in the blood or tissue of affected patients [20-26]. New knowledge of disease molecular pathology, cytogenetic, epigenetic and genomic alterations have provided new strategies to attack and eradicate tumor cells at molecular level and significantly impacted our current therapeutics for hematological malignancies. The recent and ongoing rapid WHO Classification of Tumours of Haematopoietic and Lymphoid Tissue is the third volume in the new WHO series on histological and genetic typing of human tumors. Jaffe ES, Harris NL, Stein H, Vardiman JW (2001) World Health Organization Classification of Tumors.